A New Neurobiological Model of the Human Body and Its Application to
Neuromuscular Orthodontics
Prof. Fabio Savastano, MD, DDS
Abstract
This presentation introduces a new neurobiological model of the human body that
redefines how we approach neuromuscular orthodontics. Moving beyond traditional
biomechanical views, the model incorporates concepts such as bio-tensegrity and self-
regulation to interpret the body as an interconnected, living system. At its core lies the
fascial system, once overlooked, now recognized as a crucial sensory and mechanical
interface. Recent anatomical insights, including newly identified muscular connections to the temporomandibular joint (TMJ), suggest a more intricate neuromuscular coordination than previously understood. Fascia-based mechanoreceptors provide the central nervous system with high-density proprioceptive input, influencing posture, muscle tone, and functional stability.
A clinical case is presented to illustrate the practical application of this model,
demonstrating how ultra-low frequency TENS (ULF-TENS) can help reveal neuromuscular patterns by reducing muscle memory. This approach shifts orthodontic intervention from structural correction to functional facilitation, aiming to activate the body’s innate capacity for self-regulation. By viewing the stomatognathic system within a broader postural and visceral context, clinicians are encouraged to adopt more holistic, adaptive strategies in treating occlusal and swallowing disorders. This model opens new possibilities for truly individualized, neurologically informed orthodontic care.
Learning Objectives
- To understand a holistic model of the human body and the concept of a self-
regulatory system. - To explore the use of TENS in uncovering the physiological needs of the
stomatognathic system. - To comprehend the role of functional facilitation in treatment planning.

